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Pigmentation Control

At Derma Primis, we believe true transformation starts at the cellular level. Our Pigmentation Control portfolio is built on regenerative cocktails—functional solutions that harness the skin’s natural repair processes to improve uneven tone, brighten discoloration, and prevent future pigmentation concerns. ​By combining targeted botanical actives and growth factor technology, these formulations offer patients deliver improvements in clarity and radiance.

 Regenerative Cocktails for Radiant Skin
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The Power of Growth Factors in Pigment Correction

 

​Hyperpigmentation, melasma, and post-inflammatory pigmentation are notoriously stubborn. That’s why our solutions are driven by growth factors, the skin’s own messengers of repair and regeneration. When delivered in professional cocktails and clinically matched homecare formulations optimized for pigment control, growth factors:

  • Support cellular turnover and renewal

  • Diminish pigment irregularities and dark spots

  • Strengthen skin’s barrier to prevent recurrence

  • Enhance treatment outcomes when paired with procedures like microneedling, lasers, or peels

  • This functional, science-backed approach ensures results are not only visible but sustainable.

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Partner with Derma Primis

​As the official distributor, Derma Primis provides:
  • Professional pricing and wholesale ordering

  • Clinical education and protocol support

  • Marketing materials for patient education

  • Nationwide distribution and account support

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Every growth factor has a specific function in the body, and signals the recipient cell to perform accordingly. LC Cell formulates its pigment control line up with growth factors that fade, prevent, and reduce pigment and melasma.

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Discover The LC Cell Difference

Available to medically-supervised and licensed aesthetic providers

Why Choose LC Cell Pigmentation Control Solutions?

  • Functional, regenerative cocktails that address pigment at the source

  • Growth factor science for predictable, long-lasting results

  • Synergy with professional procedures for enhanced outcomes

  • Integrated professional + homecare strategy to sustain clarity and radiance

Frequently Asked Questions

Explore our most FAQS below. Connect with a rep to answer any questions and for further information.

What are growth factors?

Small proteins or peptides that act as messenger signals between cells. They regulate healing, repair, and regeneration by binding to cell receptors and stimulating specific biological responses. Growth factors and growth factor receptors fit together in a specific way, which prevents a growth factor from binding to any receptor other than its specific target. GFs can be synthetically manufactured, bioengineered, or derived from human tissue (e.g., adipose-derived, fibroblast-derived). LC Cell's growth factors are adipose-derived from medically-screened, U.S. based donors under the age of 30.  Adipose-derived growth factors are among the most potent and clinically validated sources for skin regeneration. They are highly active in wound healing, angiogenesis (new blood vessel formation), collagen stimulation, and pigment modulation — all processes directly relevant to aesthetics.

How does LC Cell source their growth factors?

The growth factors in LC Cell products come from ethically sourced, adipose-derived tissue samples from medically-screened U.S. donors. Donors are healthy and under the age of 30. 

Where are LC Cell products made?

The LC Cell line is made in the U.S. in a FDA-cleared lab.

Who can order LC Cell products?

Medically-supervised licensed aesthetic practitioners.

What makes growth factors a superior regenerative mechanism?

Growth factors are a superior choice in the regenerative medicine space because of their safety and efficacy. When it comes to safety, growth factors contain ZERO  genetic (DNA/RNA/mRNA) or cellular matter from donors. They are not living cells—just the signals that tell cells how to behave. This makes them shelf stable, safe, and precise.

 

When it comes to efficacy, growth factors are highly specific with selective and known targets. This allows for treatment to target specific aesthetic concerns such as pigment control, deep revitalization, and hair restoration with predictable results. Additionally, the growth factors in LC Cell are of prime activity because the donors for LC Cell are under the age of 30.

What makes growth factors different from PRP?

PRP comes from a patient’s own blood and is spun in a centrifuge to isolate the plasma, which contains platelets and some growth factors. PRP is variable (depends on patient’s blood quality, age, health) and provides a broad cocktail of factors, but less concentrated and targeted compared to therapeutically specific growth factor formulations. 

What makes growth factors different from Exosomes?

Exosomes are tiny extracellular vesicles released by stem cells. They carry messenger molecules—including growth factors, RNA, and lipids—that influence how other cells function.  Exosomes can contain fragments of RNA (not DNA). These RNA molecules influence how recipient cells behave by turning certain cellular processes “on” or “off.” They shift cellular programming by changing what proteins the cell produces.  Growth factors influence cells, but they don't reprogram them; they tell cells to use their existing genetic instructions differently but they don't change which genes exist or rewrite what proteins can be made long-term. 

  • Growth factors = external messages, like a coach telling players what play to run (but the playbook is already in place).

  • Exosomes = messages plus extra playbooks (mRNA, miRNA) that can temporarily alter what the team is capable of running. While this can be regenerative, it introduces unpredictability: the same RNA payload could cause different effects in different patients or tissues. Concerns include unintended immune reactions, tumor promotion, or off-target effects.

What makes growth factors different from Stem Cells?

Stem cells  are living, undifferentiated cells capable of dividing and transforming into multiple specialized cell types. Stem cells provide both direct cell replacement and signaling (through exosomes they naturally release). In theory, they have broad regenerative potential and can rebuild damaged tissue at the cellular level.  In practice, most of their benefit comes indirectly — by secreting exosomes, cytokines, and growth factors. Stem cells pose regulatory and ethical complexities and they are not widely used in aesthetics at this time.

What makes growth factors different from PDGF?

PDGF is a specific type of growth factor which drives fibroblast proliferation, extracellular matrix remodeling, and angiogenesis. Angiogenesis is the process of forming new blood vessels from existing ones. Aesthetic providers use it for skin thickening and fine line reduction. It has a focused, but narrow effect — PDGF is excellent for dermal proliferation but doesn’t address pigment, oxidative stress, or broad anti-aging pathways.​ It is strongly proven in wound healing for diabetic patients but  is injected off-label in aesthetics.  Growth factors are a broad family of naturally occurring proteins that act as messenger signals to regulate healing, collagen production, angiogenesis, and pigmentation balance. 

How are LC Cell products used in a professional setting?

LC Cell professional cocktails are used topically in combination with microneedling or lasers. For questions about additional applications, please speak with your local representative.

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